Sponsor
RS Hasan Sadikin (RSHS) in Bandung
RS Cipto Mangunkusumo (RSCM) in Jakarta
Collaborators
Faculty of Medicine Universitas Padjajaran, Faculty of Medicine Universitas Indonesia, and OUCRU Indonesia, Radboud University
Principal Investigators
dr. Darma Imran, Sp.S(K)
dr. Sofiati Dian., SpS(K)., M.Kes., PhD
Dedeh Supantini, dr., SpS., M.Pd.Ked
Responsible Investigator
Assoc. Prof. Raph Hamers
Duration
December 2018 – ongoing
Status
Patient recruitment is ongoing at two hospitals, with about 1,100 patients enrolled so far.
The IBIS study aims to address the challenges posed by central nervous system (CNS) infections in Indonesia, such as meningitis, encephalitis, and brain abscesses. These diseases have caused significant illness and death, but their etiology has not been described well, diagnosis and treatment are often very difficult, and our understanding of risk factors and pathogenesis is incomplete.
The study collects information on CNS infections at two hospitals in Indonesia to enrich our understanding of these diseases and improve diagnosis, treatment, and intervention. The study also serves as a biorepository of patient samples for other research and may extend to other hospitals in the future.
The IBIS study seeks to describe the clinical presentation, causes, treatment, and outcomes of patients with central nervous system (CNS) infections in Indonesia.
The study initially received Dana Hibah Riset IPTEKKES funding from the Indonesian Ministry of Health in 2019 and currently receives support from the Medical Research Council and Wellcome Trust [110179/Z/15/Z].
The study has recruited 1,100 patients with suspected CNS infections at RSHS and RSCM. Data collected under this study can be and has been utilized by other studies, such as ULTIMATE, HARVEST, and ACT HIV.
