Marlous

Dr Marlous Grijsen

Senior Clinician Scientist

Dr Marlous Grijsen is a dermatologist and Senior Clinician Scientist at the Oxford University Clinical Research Unit Indonesia, focusing her research on neglected tropical skin diseases (skin-NTDs), including the stigma and discrimination associated with it. She is the lead investigator of an ongoing randomized clinical trial evaluating metformin as adjunctive therapy in multibacillary leprosy to mitigate leprosy reactions. She has established teledermatology services to improve access to care in underserved areas in eastern Indonesia and is conducting a surveillance study to assess the burden of common and neglected skin diseases in Sumba Island.

Dr Marlous Grijsen is a global health dermatologist with a diverse background in medical training and research. Trained in the Netherlands and Tanzania, she has been working as a postdoctoral research fellow at the Oxford University Clinical Research Unit Indonesia in Jakarta since 2019, after earning her PhD in Medicine from the University of Amsterdam. Her research focuses on addressing the complex challenges presented by endemic neglected tropical skin diseases within Indonesia’s rural and impoverished communities. 

In her research, Dr Grijsen explores the epidemiology, immunopathogenesis, diagnosis, and management of skin-NTDs, actively leading a phase 2 randomized trial to investigate the efficacy of adjunctive metformin in combination with standard multi-drug therapy in multibacillary leprosy to mitigate leprosy reactions (MetLep Trial, NCT05243654). This study is financially supported by the Leprosy Research Initiative and the Turing Foundation. Additionally, Dr Grijsen oversees a surveillance study on the island of Sumba to evaluate the burden of common and neglected skin diseases and has implemented a low-cost smartphone-based teledermatology service to improve access to specialized dermatological care in remote areas. Through her work, Dr. Grijsen aims to enhance healthcare delivery and reduce the stigma associated with skin-NTDs, employing participatory action research and community engagement strategies to achieve these goals. 

Timeline

2023

International Award for Social Responsibility in Dermatology by L’Oreal & ILDS – Addressing the Invisible Burden of People Affected by Leprosy and Other Neglected Skin Diseases in Eastern Indonesia.

2018

Dermatovenereologist, Leiden University Medical Center, certified by the Royal Dutch Medical Association (KNMG).

2013

PhD Medicine. University of Amsterdam, the Netherlands.

Thesis: Treatment of Primary HIV Infection. 

2006

Doctor of Medicine, Maastricht University, the Netherlands.

Publications

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Marlous L Grijsen, Thuan H Nguyen, Roberta Olmo Pinheiro, Pushpendra Singh, Saba M Lambert, Stephen L Walker, Annemieke Geluk
Nat Rev Dis Primers
November 28, 2024
DOI: 10.1038/s41572-024-00575-1
Dallas J Smith, Fl%E1vio Queiroz-Telles, Fahafahantsoa Rapelanoro Rabenja, Roderick Hay, Alexandro Bonifaz, Marlous L Grijsen, Romain Blaizot, Fernando Messina, Yinggai Song, Shawn R Lockhart, Alexander Jordan, Alyson M Cavanaugh, Anastasia P Litvintseva, Tom Chiller, Marco Schito, Sybren de Hoog, Vania Aparecida Vicente, Muriel Cornet, Daniel Argaw Dagne, Lala S Ramarozatovo, Concei%E7%E3o de Maria Pedrozo E Silva de Azevedo, Daniel Wagner C L Santos
PLoS Negl Trop Dis
October 15, 2024
DOI: 10.1371/journal.pntd.0012562
Alexis G Strahan, Olivia M T Davies, Luc%EDa T Fern%E1ndez, Inena Wa Inena Gaylord, Yared Getachew Mekonnen, Marlous L Grijsen, Jose E Ollague, Doriane Sabushimike, Luisa Polo Silveira, Toby Maurer, Roni P Dodiuk-Gad, Archana Singal, Henry W Lim, Arpita Bhose, Janet E Lubov, Shivani Jain, Morvarid Zehtab, Tom Allison, Maud Guerin, Wendemagegn Enbiale, Wingfield Rehmus, Karolyn A Wanat, L Claire Fuller, Elizabeth Bailey, Esther E Freeman
Br J Dermatol
April 26, 2024
DOI: 10.1093/bjd/ljae164
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