Projects

Dengue is known to disproportionately affect children; however, major hospitals in Vietnam still receive high numbers of admissions of patients aged 60 and above. This study investigates how ageing may influence dengue progression and the body’s response to the virus. The results aim to improve clinical treatment and inform vaccine development.

Dengue fever remains a major public health issue in Ho Chi Minh City. This study investigates the circulating dengue virus serotypes and genotypes in the city, with a focus on newly emerging lineages of Dengue Virus Serotype 2 (DENV-2), known as the Cosmopolitan strain. The results will support outbreak forecasting and strengthen prevention and control efforts.

A multi-centre randomised controlled non-inferiority trial to compare the efficacy, safety and tolerability of Triple Artemisinin-based Combination Therapies versus first-line ACTs + placebo for the treatment of uncomplicated Plasmodium falciparum malaria in Asia.

The project aimed to set up validated molecular leptospirosis diagnosis using lipl32 and secY genes, for use in settings where availability of MAT is restricted.

We aimed to promote knowledge about and interest in science and research within the community and create a platform for researchers and the public to interact, engage, and exchange their feedback.

This project aims to increase awareness of antimicrobial resistance in the user population and encourage the change of behaviour towards medically appropriate use of antibiotics. 

This project aims to assess the cost-effectiveness of Antimicrobial stewardship (AMS) programs in hospitals in Viet Nam.

This study aims to investigate the real-world effectiveness of vaccinations, including booster doses, against symptomatic COVID-19 among the general population in Indonesia.

This project aims to assess the gaps in vaccination against childhood diseases that were caused by the COVID-19 pandemic in Vietnam in 2020 and 2021.

This pivotal trial, INSPECTOR, is intended to support an application for regulatory approval by the Indonesian authorities of TQ for a radical cure of vivax malaria in Indonesia.

The aim of the MetLep Trial is to determine whether adjunctive metformin, combined with standard-of-care multi-drug therapy (MDT), could improve the clinical outcomes of patients with multibacillary leprosy by mitigating leprosy reactions and its associated nerve damage.

The Typhoid Conjugate Vaccine Trial in Nepal (TyVAC-Nepal) was a typhoid vaccination trial that took place between 2017 and 2020. Public and community engagement was integral to each aspect and stage of the trial.