Active Trial High Dose Oral Rifampicin to Improve Survival from Adult Tuberculous Meningitis (HARVEST Study) This double-blinded randomised controlled Phase III trial aims to determine if high dose rifampicin is safe and improves 6-month survival compared to standard of care for patients with Tuberculous Meningitis (TBM). Mei 3, 2023
Hospital-Wide Genomic Surveillance Of A. Baumannii Infections At A Tertiary Hospital In Vietnam In this hospital surveillance of baumannii infections, we characterised the clinical features and risk factors associated with A. baumannii-infected patients. Mei 3, 2023
Engagement|Policy Engagement How evidence is used to inform health policy in Vietnam The main goal of this study was to understand how policy stakeholders in Viet Nam used scientific evidence to inform health policies and decision making, and then to determine where there are opportunities for the scientific community (and OUCRU specifically) to better engage with policy makers to facilitate that process. November 21, 2023
Identification Of Potential Virulence Genes-Associated With Streptococcus Suis Infection In Humans Using Whole-Genome Sequencing Data Streptococcus suis is an important bacterial pathogen in pigs and also an agent of emerging severe diseases in humans. The project aims to construct a virulence gene database for S. suis which could be applied to screen for the prevalence of those potential virulence genes in the genome of S. suis strains and suggest potential virulence genes involved in the pathogenicity in humans. Mei 8, 2023
Identification Of Potential Virulence Genes-Associated With Streptococcus Suis Infection In Humans Using Whole-Genome Sequencing Data Streptococcus suis is an important bacterial pathogen in pigs and also an agent of emerging severe diseases in humans. The project aims to construct a virulence gene database for S. suis which could be applied to screen for the prevalence of those potential virulence genes in the genome of S. suis strains and suggest potential virulence genes involved in the pathogenicity in humans. Mei 8, 2023
Immunogenicity And Safety Of COVID-19 Vaccine In Vietnamese Healthcare Workers This project aims to fill some important existing gaps in knowledge about the immunogenicity of the AstraZeneca COVID-19 vaccine in Vietnamese healthcare workers and the adverse events that might arise within 48 hours after vaccination. Mei 8, 2023
Active Trial Impact of Antibiotic Treatment On Human Gut Microbiome And Novel AMR Development This is a randomised controlled trial evaluating azithromycin versus ciprofloxacin for the treatment of pediatric dysentery. Mei 8, 2023
Impact of Distance to Health Facility and Degree of Illness on Treatment Seeking Behaviour for Acute Febrile Illness in Rural Impoverished Area in Eastern Indonesia (DISTANTT) This project aims to identify perceptions and physical factors influencing health-seeking behaviours in response to fever among people living in isolated and impoverished areas. Mei 8, 2023
Impact of The COVID-19 Epidemic on Tuberculosis, HIV and Childhood Vaccination Programmes in Indonesia, and Policy and Health System Factors Fostering Programme Resilience (COHERE; COVID Health System Resilience) This study intends to assess the influence of the COVID-19 pandemic and lockdowns on TB and HIV care cascades and childhood vaccine coverage at the national and district levels in Indonesia, by important risk groups. Mei 8, 2023
Impact of Vaccination of Pregnant Women with Inactivated Vaccines on Maternal and Newborn Health and Immune Responses: A Comparative Prospective Cohort Study (PregVax) The PregVax study seeks to understand how different Covid-19 vaccines affect the health of pregnant women and their newborns, focusing on side effects, breakthrough infections, birth weight, preterm births, and immune responses. Juli 5, 2024
Antimicrobial stewardship Improving Antibiotic Prescribing Through Action Planning, Educational Interventions, And Data Feedback This project aims to investigate the feasibility and impact of establishing hospital-based antimicrobial stewardship (AMS) programs comprising action-planning, educational interventions and data feedback in two provincial-level hospitals in Viet Nam. Mei 8, 2023
Improving the Evaluation Of Severe Malaria This study will develop a biomarker-based diagnostic model of severe malaria, using easily measured biomarkers such as platelet counts and white blood counts. Mei 15, 2023